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Analytical protocol to identify local ancestry-associated molecular features in cancer

People of different ancestries vary in cancer risk and outcome, and their molecular differences may indicate sources of these variations. Determining the “local” ancestry composition at each genetic locus across ancestry-admixed populations can suggest causal associations. We present a protocol to i...

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Detalles Bibliográficos
Autores principales: Carrot-Zhang, Jian, Han, Seunghun, Zhou, Wanding, Damrauer, Jeffrey S., Kemal, Anab, Cherniack, Andrew D., Beroukhim, Rameen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456058/
https://www.ncbi.nlm.nih.gov/pubmed/34585150
http://dx.doi.org/10.1016/j.xpro.2021.100766