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Induction of IL-22-Producing CD4+ T Cells by Segmented Filamentous Bacteria Independent of Classical Th17 Cells

The intestinal microbiota modulates IL-22 production in the intestine, including the induction of IL-22-producing CD4+ T helper cells. Which specific bacteria are responsible for the induction of these cells is less well understood. Here, we demonstrate through the use of novel gnotobiotic knock-in...

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Detalles Bibliográficos
Autores principales: Roy, Urmi, de Oliveira, Rômulo S., Galvez, Eric J. C., Gronow, Achim, Basic, Marijana, Perez, Laura Garcia, Gagliani, Nicola, Bleich, Andre, Huber, Samuel, Strowig, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456099/
https://www.ncbi.nlm.nih.gov/pubmed/34566952
http://dx.doi.org/10.3389/fimmu.2021.671331