Predicting T Cell Receptor Antigen Specificity From Structural Features Derived From Homology Models of Receptor-Peptide-Major Histocompatibility Complexes

The physical interaction between the T cell receptor (TCR) and its cognate antigen causes T cells to activate and participate in the immune response. Understanding this physical interaction is important in predicting TCR binding to a target epitope, as well as potential cross-reactivity. Here, we pr...

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Detalles Bibliográficos
Autores principales: Milighetti, Martina, Shawe-Taylor, John, Chain, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456106/
https://www.ncbi.nlm.nih.gov/pubmed/34566692
http://dx.doi.org/10.3389/fphys.2021.730908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456106/
https://www.ncbi.nlm.nih.gov/pubmed/34566692
http://dx.doi.org/10.3389/fphys.2021.730908

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