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Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure

Alzheimer's disease (AD) is a progressive neurodegenerative disease with no cure. Huge efforts have been made to develop anti‐AD drugs in the past decades. However, all drug development programs for disease‐modifying therapies have failed. Possible reasons for the high failure rate include inco...

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Detalles Bibliográficos
Autores principales: Chen, Xianwei, Sun, Guoqiang, Tian, E, Zhang, Mingzi, Davtyan, Hayk, Beach, Thomas G., Reiman, Eric M., Blurton‐Jones, Mathew, Holtzman, David M., Shi, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456220/
https://www.ncbi.nlm.nih.gov/pubmed/34337898
http://dx.doi.org/10.1002/advs.202101462