RRM2 Regulates Sensitivity to Sunitinib and PD‐1 Blockade in Renal Cancer by Stabilizing ANXA1 and Activating the AKT Pathway

Renal cell carcinoma (RCC) is a malignant tumor of the kidneys. Approximately 70% of RCC cases are clear cell renal cell carcinoma with von Hippel–Lindau (VHL) gene mutation and activation of the vascular endothelial growth factor (VEGF) pathway. Tyrosine kinase inhibitors (TKIs) targeting VEGF have...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Zhang, Bin, Yu, Haixin, Zhu, Liang, Yi, Lu, Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456228/
https://www.ncbi.nlm.nih.gov/pubmed/34319001
http://dx.doi.org/10.1002/advs.202100881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456228/
https://www.ncbi.nlm.nih.gov/pubmed/34319001
http://dx.doi.org/10.1002/advs.202100881

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