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Free energy calculations shed light on the nuclear pore complex’s selective barrier nature

The nuclear pore complex (NPC) is the exclusive gateway for traffic control across the nuclear envelope. Although smaller cargoes (less than 5–9 nm in size) can freely diffuse through the NPC, the passage of larger cargoes is restricted to those accompanied by nuclear transport receptors (NTRs). Thi...

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Detalles Bibliográficos
Autores principales: Matsuda, Atsushi, Mofrad, Mohammad R.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456294/
https://www.ncbi.nlm.nih.gov/pubmed/34339633
http://dx.doi.org/10.1016/j.bpj.2021.07.025