Cargando…
Free energy calculations shed light on the nuclear pore complex’s selective barrier nature
The nuclear pore complex (NPC) is the exclusive gateway for traffic control across the nuclear envelope. Although smaller cargoes (less than 5–9 nm in size) can freely diffuse through the NPC, the passage of larger cargoes is restricted to those accompanied by nuclear transport receptors (NTRs). Thi...
Autores principales: | Matsuda, Atsushi, Mofrad, Mohammad R.K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456294/ https://www.ncbi.nlm.nih.gov/pubmed/34339633 http://dx.doi.org/10.1016/j.bpj.2021.07.025 |
Ejemplares similares
-
On the nuclear pore complex and its emerging role in cellular mechanotransduction
por: Matsuda, Atsushi, et al.
Publicado: (2022) -
Viruses Challenge Selectivity Barrier of Nuclear Pores
por: Labokha, Aksana A., et al.
Publicado: (2013) -
Characterizing Binding Interactions That Are Essential for Selective Transport through the Nuclear Pore Complex
por: Lennon, Kathleen M., et al.
Publicado: (2021) -
Nucleoporins’ exclusive amino acid sequence features regulate their transient interaction with and selectivity of cargo complexes in the nuclear pore
por: Peyro, Mohaddeseh, et al.
Publicado: (2021) -
Facilitating plasmid nuclear delivery by interfering with the selective nuclear pore barrier
por: Azzam, Ihab, et al.
Publicado: (2019)