αI-spectrin represents evolutionary optimization of spectrin for red blood cell deformability

Spectrin tetramers of the membranes of enucleated mammalian erythrocytes play a critical role in red blood cell survival in circulation. One of the spectrins, αI, emerged in mammals with enucleated red cells after duplication of the ancestral α-spectrin gene common to all animals. The neofunctionali...

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Detalles Bibliográficos
Autores principales: Hale, John, An, Xiuli, Guo, Xinhua, Gao, Erjing, Papoin, Julien, Blanc, Lionel, Hillyer, Christopher D., Gratzer, Walter, Baines, Anthony, Mohandas, Narla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456306/
https://www.ncbi.nlm.nih.gov/pubmed/34352252
http://dx.doi.org/10.1016/j.bpj.2021.07.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456306/
https://www.ncbi.nlm.nih.gov/pubmed/34352252
http://dx.doi.org/10.1016/j.bpj.2021.07.027

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