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Reaction intermediate rotation during the decarboxylation of coproheme to heme b in C. diphtheriae

Monoderm bacteria utilize coproheme decarboxylases (ChdCs) to generate heme b by a stepwise decarboxylation of two propionate groups of iron coproporphyrin III (coproheme), forming two vinyl groups. This work focuses on actinobacterial ChdC from Corynebacterium diphtheriae (CdChdC) to elucidate the...

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Detalles Bibliográficos
Autores principales: Sebastiani, Federico, Michlits, Hanna, Lier, Bettina, Becucci, Maurizio, Furtmüller, Paul G., Oostenbrink, Chris, Obinger, Christian, Hofbauer, Stefan, Smulevich, Giulietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456308/
https://www.ncbi.nlm.nih.gov/pubmed/34339636
http://dx.doi.org/10.1016/j.bpj.2021.06.042