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Reaction intermediate rotation during the decarboxylation of coproheme to heme b in C. diphtheriae
Monoderm bacteria utilize coproheme decarboxylases (ChdCs) to generate heme b by a stepwise decarboxylation of two propionate groups of iron coproporphyrin III (coproheme), forming two vinyl groups. This work focuses on actinobacterial ChdC from Corynebacterium diphtheriae (CdChdC) to elucidate the...
Autores principales: | Sebastiani, Federico, Michlits, Hanna, Lier, Bettina, Becucci, Maurizio, Furtmüller, Paul G., Oostenbrink, Chris, Obinger, Christian, Hofbauer, Stefan, Smulevich, Giulietta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456308/ https://www.ncbi.nlm.nih.gov/pubmed/34339636 http://dx.doi.org/10.1016/j.bpj.2021.06.042 |
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