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Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica

Engineering a new metabolic function in a microbial host can be limited by the availability of the relevant cofactor. For instance, in Yarrowia lipolytica, the expression of a functional nitrate reductase is precluded by the absence of molybdenum cofactor (Moco) biosynthesis. In this study, we demon...

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Detalles Bibliográficos
Autores principales: Perli, Thomas, Borodina, Irina, Daran, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456426/
https://www.ncbi.nlm.nih.gov/pubmed/34519821
http://dx.doi.org/10.1093/femsyr/foab050