Novel function of fluvastatin in attenuating oxidized low-density lipoprotein-induced endothelial cell ferroptosis in a glutathione peroxidase4- and cystine-glutamate antiporter-dependent manner

Oxidized low-density lipoprotein (ox-LDL) induces endothelial cell apoptosis and dysfunction. Statins are drugs that are clinically used to lower serum cholesterol levels, and they have been shown to exert vascular protective effects. In the present study, human umbilical vein endothelial cells were...

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Detalles Bibliográficos
Autores principales: Li, Qing, Liu, Chang, Deng, Liang, Xie, Enrui, Yadav, Nishant, Tie, Yuanyuan, Cheng, Zheng, Deng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456483/
https://www.ncbi.nlm.nih.gov/pubmed/34594412
http://dx.doi.org/10.3892/etm.2021.10710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456483/
https://www.ncbi.nlm.nih.gov/pubmed/34594412
http://dx.doi.org/10.3892/etm.2021.10710

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