A Proline Mimetic for the Design of New Stable Secondary Structures: Solvent-Dependent Amide Bond Isomerization of (S)-Indoline-2-carboxylic Acid Derivatives

[Image: see text] A thorough experimental and computational study on the conformational properties of (S)-indoline-2-carboxylic acid derivatives has been conducted. Methyl (S)-1-acetylindoline-2-carboxylate, both a mimetic of proline and phenylalanine, shows a remarkable tendency toward the cis amid...

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Detalles Bibliográficos
Autores principales: Pollastrini, Matteo, Lipparini, Filippo, Pasquinelli, Luca, Balzano, Federica, Barretta, Gloria Uccello, Pescitelli, Gennaro, Angelici, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456495/
https://www.ncbi.nlm.nih.gov/pubmed/34080867
http://dx.doi.org/10.1021/acs.joc.1c00184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456495/
https://www.ncbi.nlm.nih.gov/pubmed/34080867
http://dx.doi.org/10.1021/acs.joc.1c00184

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