Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae

Heritable variation in a gene’s expression arises from mutations impacting cis- and trans-acting components of its regulatory network. Here, we investigate how trans-regulatory mutations are distributed within the genome and within a gene regulatory network by identifying and characterizing 69 mutat...

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Detalles Bibliográficos
Autores principales: Duveau, Fabien, Vande Zande, Petra, Metzger, Brian PH, Diaz, Crisandra J, Walker, Elizabeth A, Tryban, Stephen, Siddiq, Mohammad A, Yang, Bing, Wittkopp, Patricia J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456550/
https://www.ncbi.nlm.nih.gov/pubmed/34463616
http://dx.doi.org/10.7554/eLife.67806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456550/
https://www.ncbi.nlm.nih.gov/pubmed/34463616
http://dx.doi.org/10.7554/eLife.67806

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