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Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae
Heritable variation in a gene’s expression arises from mutations impacting cis- and trans-acting components of its regulatory network. Here, we investigate how trans-regulatory mutations are distributed within the genome and within a gene regulatory network by identifying and characterizing 69 mutat...
Autores principales: | Duveau, Fabien, Vande Zande, Petra, Metzger, Brian PH, Diaz, Crisandra J, Walker, Elizabeth A, Tryban, Stephen, Siddiq, Mohammad A, Yang, Bing, Wittkopp, Patricia J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456550/ https://www.ncbi.nlm.nih.gov/pubmed/34463616 http://dx.doi.org/10.7554/eLife.67806 |
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