Intracellular functions and motile properties of bi-directional kinesin-5 Cin8 are regulated by neck linker docking

In this study, we analyzed intracellular functions and motile properties of neck-linker (NL) variants of the bi-directional S. cerevisiae kinesin-5 motor, Cin8. We also examined – by modeling – the configuration of H-bonds during NL docking. Decreasing the number of stabilizing H-bonds resulted in p...

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Detalles Bibliográficos
Autores principales: Goldstein-Levitin, Alina, Pandey, Himanshu, Allhuzaeel, Kanary, Kass, Itamar, Gheber, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456603/
https://www.ncbi.nlm.nih.gov/pubmed/34387192
http://dx.doi.org/10.7554/eLife.71036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456603/
https://www.ncbi.nlm.nih.gov/pubmed/34387192
http://dx.doi.org/10.7554/eLife.71036

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