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The influence of the gut microbiome on BCG-induced trained immunity

BACKGROUND: The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome is increasingly recognized as an important modulator of vac...

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Detalles Bibliográficos
Autores principales: Stražar, Martin, Mourits, Vera P., Koeken, Valerie A. C. M., de Bree, L. Charlotte J., Moorlag, Simone J. C. F. M., Joosten, Leo A. B., van Crevel, Reinout, Vlamakis, Hera, Netea, Mihai G., Xavier, Ramnik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456614/
https://www.ncbi.nlm.nih.gov/pubmed/34551799
http://dx.doi.org/10.1186/s13059-021-02482-0