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The influence of the gut microbiome on BCG-induced trained immunity
BACKGROUND: The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome is increasingly recognized as an important modulator of vac...
Autores principales: | Stražar, Martin, Mourits, Vera P., Koeken, Valerie A. C. M., de Bree, L. Charlotte J., Moorlag, Simone J. C. F. M., Joosten, Leo A. B., van Crevel, Reinout, Vlamakis, Hera, Netea, Mihai G., Xavier, Ramnik J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456614/ https://www.ncbi.nlm.nih.gov/pubmed/34551799 http://dx.doi.org/10.1186/s13059-021-02482-0 |
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