High potency of sequential therapy with only β-lactam antibiotics

Evolutionary adaptation is a major source of antibiotic resistance in bacterial pathogens. Evolution-informed therapy aims to constrain resistance by accounting for bacterial evolvability. Sequential treatments with antibiotics that target different bacterial processes were previously shown to limit...

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Detalles Bibliográficos
Autores principales: Batra, Aditi, Roemhild, Roderich, Rousseau, Emilie, Franzenburg, Sören, Niemann, Stefan, Schulenburg, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456660/
https://www.ncbi.nlm.nih.gov/pubmed/34318749
http://dx.doi.org/10.7554/eLife.68876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456660/
https://www.ncbi.nlm.nih.gov/pubmed/34318749
http://dx.doi.org/10.7554/eLife.68876

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