Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development

Microtubules that assemble the mitotic spindle are generated by centrosomal nucleation, chromatin-mediated nucleation, and nucleation from the surface of other microtubules mediated by the augmin complex. Impairment of centrosomal nucleation in apical progenitors of the developing mouse brain induce...

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Detalles Bibliográficos
Autores principales: Viais, Ricardo, Fariña-Mosquera, Marcos, Villamor-Payà, Marina, Watanabe, Sadanori, Palenzuela, Lluís, Lacasa, Cristina, Lüders, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456695/
https://www.ncbi.nlm.nih.gov/pubmed/34427181
http://dx.doi.org/10.7554/eLife.67989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456695/
https://www.ncbi.nlm.nih.gov/pubmed/34427181
http://dx.doi.org/10.7554/eLife.67989

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