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Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development
Microtubules that assemble the mitotic spindle are generated by centrosomal nucleation, chromatin-mediated nucleation, and nucleation from the surface of other microtubules mediated by the augmin complex. Impairment of centrosomal nucleation in apical progenitors of the developing mouse brain induce...
Autores principales: | Viais, Ricardo, Fariña-Mosquera, Marcos, Villamor-Payà, Marina, Watanabe, Sadanori, Palenzuela, Lluís, Lacasa, Cristina, Lüders, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456695/ https://www.ncbi.nlm.nih.gov/pubmed/34427181 http://dx.doi.org/10.7554/eLife.67989 |
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