Myosin-X and talin modulate integrin activity at filopodia tips

Filopodia assemble unique integrin-adhesion complexes to sense the extracellular matrix. However, the mechanisms of integrin regulation in filopodia are poorly defined. Here, we report that active integrins accumulate at the tip of myosin-X (MYO10)-positive filopodia, while inactive integrins are un...

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Detalles Bibliográficos
Autores principales: Miihkinen, Mitro, Grönloh, Max L.B., Popović, Ana, Vihinen, Helena, Jokitalo, Eija, Goult, Benjamin T., Ivaska, Johanna, Jacquemet, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456781/
https://www.ncbi.nlm.nih.gov/pubmed/34525374
http://dx.doi.org/10.1016/j.celrep.2021.109716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456781/
https://www.ncbi.nlm.nih.gov/pubmed/34525374
http://dx.doi.org/10.1016/j.celrep.2021.109716

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