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Local recovery of cardiac calcium‐induced calcium release interrogated by ultra‐effective, two‐photon uncaging of calcium

KEY POINTS: In cardiac myocytes, subcellular local calcium release signals, calcium sparks, are recruited to form each cellular calcium transient and activate the contractile machinery. Abnormal timing of recovery of sparks after their termination may contribute to arrhythmias. We developed a method...

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Detalles Bibliográficos
Autores principales: Janicek, Radoslav, Agarwal, Hitesh, Gómez, Ana M., Egger, Marcel, Ellis‐Davies, Graham C. R., Niggli, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456848/
https://www.ncbi.nlm.nih.gov/pubmed/34245001
http://dx.doi.org/10.1113/JP281482