Efficacy and Safety of Diclofenac–Hyaluronate Conjugate (Diclofenac Etalhyaluronate) for Knee Osteoarthritis: A Randomized Phase III Trial in Japan

OBJECTIVE: To confirm the efficacy and safety of intraarticular (IA) injection of diclofenac covalently linked to hyaluronic acid (diclofenac etalhyaluronate [DF‐HA]; ONO‐5704/SI‐613) in patients with knee osteoarthritis (OA). METHODS: In a phase III multicenter, randomized, double‐blind, placebo‐co...

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Detalles Bibliográficos
Autores principales: Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Osteoarthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456865/
https://www.ncbi.nlm.nih.gov/pubmed/33749997
http://dx.doi.org/10.1002/art.41725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456865/
https://www.ncbi.nlm.nih.gov/pubmed/33749997
http://dx.doi.org/10.1002/art.41725

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