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Chemoenzymatic Synthesis of Complex N‐Glycans of the Parasite S. mansoni to Examine the Importance of Epitope Presentation on DC‐SIGN recognition

The importance of multivalency for N‐glycan‐protein interactions has primarily been studied by attachment of minimal epitopes to artificial multivalent scaffold and not in the context of multi‐antennary glycans. N‐glycans can be modified by bisecting GlcNAc, core xylosides and fucosides, and extende...

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Detalles Bibliográficos
Autores principales: Srivastava, Apoorva D., Unione, Luca, Bunyatov, Mehman, Gagarinov, Ivan A., Delgado, Sandra, Abrescia, Nicola G. A., Ardá, Ana, Boons, Geert‐Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456914/
https://www.ncbi.nlm.nih.gov/pubmed/34124805
http://dx.doi.org/10.1002/anie.202105647