The Binding Pocket at the Interface of Multimeric Telomere G‐quadruplexes: Myth or Reality?

Human telomeric DNA with hundreds of repeats of the 5’‐TTAGGG‐3’ motif plays a crucial role in several biological processes. It folds into G‐quadruplex (G4) structures and features a pocket at the interface of two contiguous G4 blocks. Up to now no structural NMR and crystallographic data are availa...

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Detalles Bibliográficos
Autores principales: Manoli, Francesco, Doria, Filippo, Colombo, Giorgio, Zambelli, Barbara, Freccero, Mauro, Manet, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456957/
https://www.ncbi.nlm.nih.gov/pubmed/34152657
http://dx.doi.org/10.1002/chem.202101486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456957/
https://www.ncbi.nlm.nih.gov/pubmed/34152657
http://dx.doi.org/10.1002/chem.202101486

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