Cargando…
Selective Bacterial Targeting and Infection‐Triggered Release of Antibiotic Colistin Conjugates
In order to render potent, but toxic antibiotics more selective, we have explored a novel conjugation strategy that includes drug accumulation followed by infection‐triggered release of the drug. Bacterial targeting was achieved using a modified fragment of the human antimicrobial peptide ubiquicidi...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456958/ https://www.ncbi.nlm.nih.gov/pubmed/34097810 http://dx.doi.org/10.1002/anie.202104921 |