Cargando…
Remote Site‐Selective Radical C(sp(3))−H Monodeuteration of Amides using D(2)O
Site‐selective incorporation of deuterium into biologically active compounds is of high interest in pharmaceutical industry. We present a mild and environmentally benign metal‐free method for the remote selective radical C−H monodeuteration of aliphatic C−H bonds in various amides with inexpensive h...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456965/ https://www.ncbi.nlm.nih.gov/pubmed/34114304 http://dx.doi.org/10.1002/anie.202104254 |