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Inclusion Complexes of Gold(I)‐Dithiocarbamates with β‐Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery

The gold(I)‐dithiocarbamate (dtc) complex [Au(N,N‐diethyl)dtc](2) was identified as the active cytotoxic agent in the combination treatment of sodium aurothiomalate and disulfiram on a panel of cancer cell lines. In addition to demonstrating pronounced differential cytotoxicity to these cell lines,...

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Detalles Bibliográficos
Autores principales: Morgen, Michael, Fabrowski, Piotr, Amtmann, Eberhard, Gunkel, Nikolas, Miller, Aubry K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456977/
https://www.ncbi.nlm.nih.gov/pubmed/34114261
http://dx.doi.org/10.1002/chem.202101366