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Inclusion Complexes of Gold(I)‐Dithiocarbamates with β‐Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery
The gold(I)‐dithiocarbamate (dtc) complex [Au(N,N‐diethyl)dtc](2) was identified as the active cytotoxic agent in the combination treatment of sodium aurothiomalate and disulfiram on a panel of cancer cell lines. In addition to demonstrating pronounced differential cytotoxicity to these cell lines,...
Autores principales: | Morgen, Michael, Fabrowski, Piotr, Amtmann, Eberhard, Gunkel, Nikolas, Miller, Aubry K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456977/ https://www.ncbi.nlm.nih.gov/pubmed/34114261 http://dx.doi.org/10.1002/chem.202101366 |
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