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High Frequency Mutations in pfdhfr and pfdhps of Plasmodium falciparum in Response to Sulfadoxine-Pyrimethamine: A Cross-Sectional Survey in Returning Chinese Migrants From Africa

BACKGROUND: Sulfadoxine-pyrimethamine (SP) is recommended for intermittent preventive treatment in Africa against Plasmodium falciparum infection. However, increasing SP resistance (SPR) of P. falciparum affects the therapeutic efficacy of SP, and pfdhfr (encoding dihydrofolate reductase) and pfdhps...

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Detalles Bibliográficos
Autores principales: Yan, He, Feng, Jun, Yin, Jian-hai, Huang, Fang, Kong, Xiang-li, Lin, Kang-ming, Zhang, Tao, Feng, Xin-yu, Zhou, Shui-sen, Cao, Jian-ping, Xia, Zhi-gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456993/
https://www.ncbi.nlm.nih.gov/pubmed/34568082
http://dx.doi.org/10.3389/fcimb.2021.673194