Cargando…

tRNA-like leader-trailer interaction promotes 3′-end maturation of MALAT1

Human metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a nuclear long noncoding RNA (lncRNA) that is highly overexpressed in many cancer tissues and plays important roles in tumor progression and metastasis. The MALAT1 primary transcript contains evolutionarily conserved structural...

Descripción completa

Detalles Bibliográficos
Autores principales: Torabi, Seyed-Fakhreddin, DeGregorio, Suzanne J., Steitz, Joan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457004/
https://www.ncbi.nlm.nih.gov/pubmed/34253686
http://dx.doi.org/10.1261/rna.078810.121