Comparative study on tertiary contacts and folding of RNase P RNAs from a psychrophilic, a mesophilic/radiation-resistant, and a thermophilic bacterium

In most bacterial type A RNase P RNAs (P RNAs), two major loop-helix tertiary contacts (L8–P4 and L18–P8) help to orient the two independently folding S- and C-domains for concerted recognition of precursor tRNA substrates. Here, we analyze the effects of mutations in these tertiary contacts in P RN...

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Detalles Bibliográficos
Autores principales: Marszalkowski, Michal, Werner, Andreas, Feltens, Ralph, Helmecke, Dominik, Gößringer, Markus, Westhof, Eric, Hartmann, Roland K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457005/
https://www.ncbi.nlm.nih.gov/pubmed/34266994
http://dx.doi.org/10.1261/rna.078735.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457005/
https://www.ncbi.nlm.nih.gov/pubmed/34266994
http://dx.doi.org/10.1261/rna.078735.121

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