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FLAME: long-read bioinformatics tool for comprehensive spliceome characterization

Comprehensive characterization of differentially spliced RNA transcripts with nanopore sequencing is limited by bioinformatics tools that are reliant on existing annotations. We have developed FLAME, a bioinformatics pipeline for alternative splicing analysis of gene-specific or transcriptome-wide l...

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Detalles Bibliográficos
Autores principales: Holmqvist, Isak, Bäckerholm, Alan, Tian, Yarong, Xie, Guojiang, Thorell, Kaisa, Tang, Ka-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457008/
https://www.ncbi.nlm.nih.gov/pubmed/34253685
http://dx.doi.org/10.1261/rna.078800.121