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QSAR modeling and docking analysis of D2 receptor with known olanzapine derivatives

Dopamine (D2) receptors are known drug targets for various antipsychotics used in Schizophrenia. Therefore, it is of interest to analyze the binding features of D2 receptors with known olanzapine derivatives for further consideration using molecular docking and QSAR analysis. A 2D QSAR model was bui...

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Detalles Bibliográficos
Autores principales: Bhargava, Kiran, Seth, Prahlad Kishore, Pant, Kamlesh Kumar, Dixit, Rakesh Kumar, Agarwal, Vivek, Sawlanid, Kamal Kumar, Nath, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457016/
https://www.ncbi.nlm.nih.gov/pubmed/34621111
http://dx.doi.org/10.6026/97320630016666