Highly efficient manipulation of nervous system gene expression with NEPTUNE

Genetic loss and gain of function in mice have typically been studied by using knockout or knockin mice that take months to years to generate. To address this problem for the nervous system, we developed NEPTUNE (NEural Plate Targeting by in Utero NanoinjEction) to rapidly and flexibly transduce the...

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Detalles Bibliográficos
Autores principales: Mangold, Katrin, Mašek, Jan, He, Jingyan, Lendahl, Urban, Fuchs, Elaine, Andersson, Emma R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457050/
https://www.ncbi.nlm.nih.gov/pubmed/34557863
http://dx.doi.org/10.1016/j.crmeth.2021.100043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457050/
https://www.ncbi.nlm.nih.gov/pubmed/34557863
http://dx.doi.org/10.1016/j.crmeth.2021.100043

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