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RNA‐Cleaving Deoxyribozymes Differentiate Methylated Cytidine Isomers in RNA

Deoxyribozymes are emerging as modification‐specific endonucleases for the analysis of epigenetic RNA modifications. Here, we report RNA‐cleaving deoxyribozymes that differentially respond to the presence of natural methylated cytidines, 3‐methylcytidine (m(3)C), N (4)‐methylcytidine (m(4)C), and 5‐...

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Detalles Bibliográficos
Autores principales: Liaqat, Anam, Sednev, Maksim V., Stiller, Carina, Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457104/
https://www.ncbi.nlm.nih.gov/pubmed/34185947
http://dx.doi.org/10.1002/anie.202106517