From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein‐Templated Synthesis

Multitarget directed ligands (MTDLs) are arising as promising tools to tackle complex diseases. The main goal of this work is to create powerful modulating agents for neurodegenerative disorders. To achieve this aim, we have combined fragments that inhibit key protein kinases involved in the main pa...

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Detalles Bibliográficos
Autores principales: Nozal, Vanesa, García‐Rubia, Alfonso, Cuevas, Eva P., Pérez, Concepción, Tosat‐Bitrián, Carlota, Bartolomé, Fernando, Carro, Eva, Ramírez, David, Palomo, Valle, Martínez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457121/
https://www.ncbi.nlm.nih.gov/pubmed/34169618
http://dx.doi.org/10.1002/anie.202106295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457121/
https://www.ncbi.nlm.nih.gov/pubmed/34169618
http://dx.doi.org/10.1002/anie.202106295

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