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Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes‐1 negatively regulates human neutrophils

Signal inhibitory receptor on leukocytes‐1 (SIRL‐1) is an inhibitory receptor with a hitherto unknown ligand, and is expressed on human monocytes and neutrophils. SIRL‐1 inhibits myeloid effector functions such as reactive oxygen species (ROS) production. In this study, we identify S100 proteins as...

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Detalles Bibliográficos
Autores principales: Rumpret, Matevž, von Richthofen, Helen J., van der Linden, Maarten, Westerlaken, Geertje H. A., Talavera Ormeño, Cami, Low, Teck Y., Ovaa, Huib, Meyaard, Linde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457157/
https://www.ncbi.nlm.nih.gov/pubmed/34145909
http://dx.doi.org/10.1002/eji.202149278