Cryo‐electron Microscopy Imaging of Alzheimer's Amyloid‐beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold

Amyloid‐β peptide (Aβ) oligomers are pathogenic species of amyloid aggregates in Alzheimer's disease. Like certain protein toxins, Aβ oligomers permeabilize cellular membranes, presumably through a pore formation mechanism. Owing to their structural and stoichiometric heterogeneity, the structu...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jinming, Blum, Thorsten B., Farrell, Daniel P, DiMaio, Frank, Abrahams, Jan Pieter, Luo, Jinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457241/
https://www.ncbi.nlm.nih.gov/pubmed/34042235
http://dx.doi.org/10.1002/anie.202104497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457241/
https://www.ncbi.nlm.nih.gov/pubmed/34042235
http://dx.doi.org/10.1002/anie.202104497

Ejemplares similares