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Photoprocesses of the tyrosine kinase inhibitor gefitinib: from femtoseconds to microseconds and from solution to cells

Gefitinib (GFT) is a tyrosine kinase inhibitor currently used for the treatment of metastatic non-small cell lung cancer. Although it has been suggested that GFT can be phototoxic, there are no systematic studies on this issue. Here, the photosensitizing potential of GFT has been assessed by means o...

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Detalles Bibliográficos
Autores principales: Tamarit, Lorena, El Ouardi, Meryem, Andreu, Inmaculada, Vayá, Ignacio, Miranda, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457384/
https://www.ncbi.nlm.nih.gov/pubmed/34667568
http://dx.doi.org/10.1039/d1sc03154f