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The PPLD has advantages over conventional regression methods in application to moderately sized genome-wide association studies

In earlier work, we have developed and evaluated an alternative approach to the analysis of GWAS data, based on a statistic called the PPLD. More recently, motivated by a GWAS for genetic modifiers of the X-linked Mendelian disorder Duchenne Muscular Dystrophy (DMD), we adapted the PPLD for applicat...

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Detalles Bibliográficos
Autores principales: Vieland, Veronica J., Seok, Sang-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457474/
https://www.ncbi.nlm.nih.gov/pubmed/34550985
http://dx.doi.org/10.1371/journal.pone.0257164