Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway

Exaggerated inflammatory response results in pathogenesis of various inflammatory diseases. Tumor Necrosis Factor-alpha (TNF) is a multi-functional pro-inflammatory cytokine regulating a wide spectrum of physiological, biological, and cellular processes. TNF induces Focal Adhesion Kinase (FAK) for v...

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Detalles Bibliográficos
Autores principales: Pokharel, Swechha M., Chiok, Kim, Shil, Niraj K., Mohanty, Indira, Bose, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457477/
https://www.ncbi.nlm.nih.gov/pubmed/34551004
http://dx.doi.org/10.1371/journal.pone.0257576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457477/
https://www.ncbi.nlm.nih.gov/pubmed/34551004
http://dx.doi.org/10.1371/journal.pone.0257576

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