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Exogene: A performant workflow for detecting viral integrations from paired-end next-generation sequencing data
The integration of viruses into the human genome is known to be associated with tumorigenesis in many cancers, but the accurate detection of integration breakpoints from short read sequencing data is made difficult by human-viral homologies, viral genome heterogeneity, coverage limitations, and othe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457494/ https://www.ncbi.nlm.nih.gov/pubmed/34550971 http://dx.doi.org/10.1371/journal.pone.0250915 |