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Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice

Non-convulsive epileptiform activity is a common and under-studied comorbidity of Alzheimer’s disease that may significantly contribute to onset of clinical symptoms independently of other neuropathological features such as β-amyloid deposition. We used repeated treatment with low dose kainic acid (...

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Detalles Bibliográficos
Autores principales: Wilcox, J.M., Consoli, D.C., Tienda, A.A., Dixit, S., Buchanan, R.A., May, J.M., Nobis, W. P., Harrison, F.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457528/
https://www.ncbi.nlm.nih.gov/pubmed/34450329
http://dx.doi.org/10.1016/j.nbd.2021.105486