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Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism
Temozolomide (TMZ) is used for the treatment of high-grade gliomas. Acquired chemoresistance is a serious limitation to the therapy with more than 90% of recurrent gliomas showing little response to a second line of chemotherapy. Therefore, it is necessary to explore an alternative strategy to enhan...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457578/ https://www.ncbi.nlm.nih.gov/pubmed/34497154 http://dx.doi.org/10.18632/aging.203443 |