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Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism

Temozolomide (TMZ) is used for the treatment of high-grade gliomas. Acquired chemoresistance is a serious limitation to the therapy with more than 90% of recurrent gliomas showing little response to a second line of chemotherapy. Therefore, it is necessary to explore an alternative strategy to enhan...

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Detalles Bibliográficos
Autores principales: Yin, Delong, Jin, Guoqing, He, Hong, Zhou, Wei, Fan, Zhenbo, Gong, Chen, Zhao, Jing, Xiong, Huihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457578/
https://www.ncbi.nlm.nih.gov/pubmed/34497154
http://dx.doi.org/10.18632/aging.203443