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UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma

Most EEC cases are associated with activities of the mTOR pathway, which regulates protein synthesis, cell growth and autophagy. While Up-Frameshift 1(UPF1) is a key protein factor in the nonsense-mediated mRNA degradation pathway (NMD), its role in carcinogenesis of EEC remains unclear. In this stu...

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Detalles Bibliográficos
Autores principales: Zhang, Minfen, Chen, Hui, Qin, Ping, Cai, Tonghui, Li, Lingjun, Chen, Ruichao, Liu, Shaoyan, Lin, Wanrun, Chen, Hao, Strickland, Amanda L., Xiong, Hanzhen, Jiang, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457587/
https://www.ncbi.nlm.nih.gov/pubmed/34520393
http://dx.doi.org/10.18632/aging.203421