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UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma
Most EEC cases are associated with activities of the mTOR pathway, which regulates protein synthesis, cell growth and autophagy. While Up-Frameshift 1(UPF1) is a key protein factor in the nonsense-mediated mRNA degradation pathway (NMD), its role in carcinogenesis of EEC remains unclear. In this stu...
Autores principales: | Zhang, Minfen, Chen, Hui, Qin, Ping, Cai, Tonghui, Li, Lingjun, Chen, Ruichao, Liu, Shaoyan, Lin, Wanrun, Chen, Hao, Strickland, Amanda L., Xiong, Hanzhen, Jiang, Qingping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457587/ https://www.ncbi.nlm.nih.gov/pubmed/34520393 http://dx.doi.org/10.18632/aging.203421 |
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