Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis

In this study, we investigated the mechanisms through which astrocyte-derived exosomes (AS-Exos) alleviate traumatic brain injury (TBI)-induced neuronal defects in TBI model rats and mice. Treatment with AS-Exos alleviated neurobehavioral deficits, cognitive impairment, and brain edema in TBI rats....

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Detalles Bibliográficos
Autores principales: Zhang, Wenqian, Hong, Jun, Zhang, Hanwen, Zheng, Wencheng, Yang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457605/
https://www.ncbi.nlm.nih.gov/pubmed/34516406
http://dx.doi.org/10.18632/aging.203508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457605/
https://www.ncbi.nlm.nih.gov/pubmed/34516406
http://dx.doi.org/10.18632/aging.203508

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