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Kinetic analysis of the inhibition mechanism of bovine mitochondrial F(1)-ATPase inhibitory protein using biochemical assay

ATPase inhibitory factor 1 (IF(1)) is a mitochondrial regulatory protein that blocks ATP hydrolysis of F(1)-ATPase, by inserting its N-terminus into the rotor–stator interface of F(1)-ATPase. Although previous studies have proposed a two-step model for IF(1)-mediated inhibition, the underlying molec...

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Detalles Bibliográficos
Autores principales: Kobayashi, Ryohei, Mori, Sougo, Ueno, Hiroshi, Noji, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457647/
https://www.ncbi.nlm.nih.gov/pubmed/33693769
http://dx.doi.org/10.1093/jb/mvab022